Overexpression of Aurora-A in primary cells interferes with S-phase entry by diminishing Cyclin D1 dependent activities
Abstract Background Aurora-A is a bona-fide oncogene whose expression is associated with genomic instability and malignant transformation.In several types of cancer, gene amplification and/or increased protein levels of Aurora-A are a common feature.Results In this report, we describe Electric Fireplace that inhibition of cell proliferation is the